IUBMB Enzyme Nomenclature

EC 1.10.3.12

Accepted name: menaquinol oxidase (H+-transporting)

Reaction: 2 menaquinol + O2 = 2 menaquinone + 2 H2O

Other name(s): cytochrome aa3-600 oxidase; cytochrome bd oxidase; menaquinol:O2 oxidoreductase (H+-transporting)

Systematic name: menaquinol:oxygen oxidoreductase (H+-transporting)

Comments: Cytochrome aa3-600, one of the principal respiratory oxidases from Bacillus subtilis, is a member of the heme-copper superfamily of oxygen reductases, and is a close homologue of the cytochrome bo3 ubiquinol oxidase from Escherichia coli, but uses menaquinol instead of ubiquinol as a substrate. The enzyme also pumps protons across the membrane bilayer, generating a proton motive force.

Links to other databases: BRENDA, EXPASY, KEGG, Metacyc, CAS registry number:

References:

1. Lauraeus, M. and Wikstrom, M. The terminal quinol oxidases of Bacillus subtilis have different energy conservation properties. J. Biol. Chem. 268 (1993) 11470-11473. [PMID: 8388393]

2. Lemma, E., Simon, J., Schagger, H. and Kroger, A. Properties of the menaquinol oxidase (Qox) and of qox deletion mutants of Bacillus subtilis. Arch. Microbiol. 163 (1995) 432-438. [PMID: 7575098]

3. Yi, S.M., Narasimhulu, K.V., Samoilova, R.I., Gennis, R.B. and Dikanov, S.A. Characterization of the semiquinone radical stabilized by the cytochrome aa3-600 menaquinol oxidase of Bacillus subtilis. J. Biol. Chem. 285 (2010) 18241-18251. [PMID: 20351111]

[EC 1.10.3.12 created 2011]


Return to EC 1.10.3 home page
Return to EC 1.10 home page
Return to EC 1 home page
Return to Enzymes home page
Return to IUBMB Biochemical Nomenclature home page