Reaction: an (S)-2-hydroxy carboxylate + O2 = a 2-oxo carboxylate + H2O2
Other name(s): glycolate oxidase; hydroxy-acid oxidase A; hydroxy-acid oxidase B; glycolate oxidase; oxidase, L-2-hydroxy acid; hydroxyacid oxidase A; L-α-hydroxy acid oxidase; L-2-hydroxy acid oxidase
Systematic name: (S)-2-hydroxy-acid:oxygen 2-oxidoreductase
Comments: A flavoprotein (FMN). Exists as two major isoenzymes; the A form preferentially oxidizes short-chain aliphatic hydroxy acids, and was previously listed as EC 220.127.116.11, glycolate oxidase; the B form preferentially oxidizes long-chain and aromatic hydroxy acids. The rat isoenzyme B also acts as EC 18.104.22.168, L-amino-acid oxidase.
Links to other databases: BRENDA, EXPASY, KEGG, Metacyc, PDB, CAS registry number: 9028-71-1
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