Reaction: propan-2-ol + NADP+ = acetone + NADPH + H+
Other name(s): isopropanol dehydrogenase (NADP)
Systematic name: propan-2-ol:NADP+ oxidoreductase
Comments: Also acts on other short-chain secondary alcohols and, slowly, on primary alcohols.
Links to other databases: BRENDA, EXPASY, KEGG, Metacyc, PDB, CAS registry number: 37250-18-3
References:
1. Hoshino, K. Organism producing isopropanol from acetone. V. Enzymological [studies] on the oxidation-reduction of Lactobacillus brevis var. hofuensis. [in Japanese] Nippon Nogei Kagaku Kaishi 34 (1960) 608-615.
2. Hoshino, K. and Udagawa, K. Organism producing isopropanol from acetone. VI. Isopropanol dehydrogenase and alcohol dehydrogenase of Lactobacillus brevis var. hofuensis. [in Japanese] Nippon Nogei Kagaku Kaishi 34 (1960) 616-619.