IUBMB Enzyme Nomenclature

EC 1.1.1.385

Accepted name: dihydroanticapsin dehydrogenase

Reaction: L-dihydroanticapsin + NAD+ = L-anticapsin + NADH + H+

For diagram of reaction click here.

Glossary: L-dihydroanticapsin = 3-[(1R,2S,5R,6S)-5-hydroxy-7-oxabicyclo[4.1.0]hept-2-yl]-L-alanine
L-anticapsin = 3-[(1R,2S,6R)-5-oxo-7-oxabicyclo[4.1.0]hept-2-yl]-L-alanine

Other name(s): BacC; ywfD (gene name)

Systematic name: L-dihydroanticapsin:NAD+ oxidoreductase

Comments: The enzyme, characterized from the bacterium Bacillus subtilis, is involved in the biosynthesis of the nonribosomally synthesized dipeptide antibiotic bacilysin, composed of L-alanine and L-anticapsin.

Links to other databases: BRENDA, EXPASY, KEGG, MetaCyc, CAS registry number:

References:

1. Parker, J.B. and Walsh, C.T. Action and timing of BacC and BacD in the late stages of biosynthesis of the dipeptide antibiotic bacilysin. Biochemistry 52 (2013) 889-901. [PMID: 23317005]

[EC 1.1.1.385 created 2015]


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