Reaction: scyllo-inositol + NADP+ = 2,4,6/3,5-pentahydroxycyclohexanone + NADPH + H+
For diagram of reaction click here.
Glossary: 2,4,6/3,5-pentahydroxycyclohexanone = (2R,3S,4s,5R,6S)-2,3,4,5,6-pentahydroxycyclohexanone = scyllo-inosose
Other name(s): iolW (gene name)
Systematic name: scyllo-inositol:NADP+ 2-oxidoreductase
Comments: The enzyme, found in the bacterium Bacillus subtilis, has no activity with NAD+ [cf. EC 220.127.116.110, scyllo-inositol 2-dehydrogenase (NAD+)].
Links to other databases: BRENDA, EXPASY, KEGG, Metacyc, CAS registry number:
1. Morinaga, T., Ashida, H. and Yoshida, K. Identification of two scyllo-inositol dehydrogenases in Bacillus subtilis. Microbiology 156 (2010) 1538-1546. [PMID: 20133360]