Reaction: (2E,6E)-farnesol + NAD+ = (2E,6E)-farnesal + NADH + H+
For diagram of reaction click here.
Other name(s): NAD+-farnesol dehydrogenase
Systematic name: (2E,6E)-farnesol:NAD+ 1-oxidoreductase
Comments: The enzyme from the prune mite Carpoglyphus lactis also acts on geraniol with greater activity [cf. EC 126.96.36.1997, geraniol dehydrogenase (NAD+)]. Unlike EC 188.8.131.52, farnesol dehydrogenase (NADP+), this enzyme cannot use NADP+ as cofactor.
Links to other databases: BRENDA, EXPASY, KEGG Metacyc, CAS registry number:
1. Noge, K., Kato, M., Mori, N., Kataoka, M., Tanaka, C., Yamasue, Y., Nishida, R. and Kuwahara, Y. Geraniol dehydrogenase, the key enzyme in biosynthesis of the alarm pheromone, from the astigmatid mite Carpoglyphus lactis (Acari: Carpoglyphidae). FEBS J. 275 (2008) 2807-2817. [PMID: 18422649]