Reaction: 5-exo-hydroxycamphor + NAD+ = bornane-2,5-dione + NADH + H+
For diagram of reaction click here.
Other name(s): F-dehydrogenase; FdeH
Systematic name: 5-exo-hydroxycamphor:NADP+ oxidoreductase
Comments: Contains Zn2+. Isolated from Pseudomonas putida, and involved in degradation of (+)-camphor.
Links to other databases: BRENDA, EAWAG-BBD, EXPASY, KEGG, Metacyc, CAS registry number:
References:
1. Rheinwald, J.G., Chakrabarty, A.M. and Gunsalus, I.C. A transmissible plasmid controlling camphor oxidation in Pseudomonas putida. Proc. Natl. Acad. Sci. USA 70 (1973) 885-889. [PMID: 4351810]
2. Koga, H., Yamaguchi, E., Matsunaga, K., Aramaki, H. and Horiuchi, T. Cloning and nucleotide sequences of NADH-putidaredoxin reductase gene (camA) and putidaredoxin gene (camB) involved in cytochrome P-450cam hydroxylase of Pseudomonas putida. J. Biochem. 106 (1989) 831-836. [PMID: 2613690]
3. Aramaki, H., Koga, H., Sagara, Y., Hosoi, M. and Horiuchi, T. Complete nucleotide sequence of the 5-exo-hydroxycamphor dehydrogenase gene on the CAM plasmid of Pseudomonas putida (ATCC 17453). Biochim. Biophys. Acta 1174 (1993) 91-94. [PMID: 8334169]