Reaction: (R)-pantoate + NADP+ = 2-dehydropantoate + NADPH + H+
For diagram of reaction click here.
Glossary:
pantoate = 2,4-dihydroxy-3,3-dimethylbutanoate
Other name(s): 2-oxopantoate reductase; 2-ketopantoate reductase; 2-ketopantoic acid reductase; ketopantoate reductase; ketopantoic acid reductase
Systematic name: (R)-pantoate:NADP+ 2-oxidoreductase
Links to other databases: BRENDA, EXPASY, KEGG, Metacyc, PDB, CAS registry number: 37211-74-8
References:
1. King, H.L., Jr. and Wilken, D.R. Ketopantoyl lactone and ketopantoic acid reductases. Characterization of the reactions and purification of two forms of ketopantoyl lactone reductase. J. Biol. Chem. 247 (1972) 4689-4695.